"I do not know what I may appear to the world; but to myself I seem to have been only like a boy playing on the seashore, and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, while the great ocean of truth lay all undiscovered before me."
Sir Isaac Newton
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Our scientific goal to integrate proteomics and genomics biology of inflammation with care of the injured patient can only be realized through the integration and simultaneous accomplishment of multiple tasks. These tasks include:
To fill the gaps in trauma research, the large-scale collaborative program has been organized into several components, each distinctly different, yet highly interrelated to provide a networked approach of interactions. There are several clinical studies in which trauma and burn patients, and LPS-challenged and normal volunteers, as well as other appropriate models, are studied to generate data and samples for physiological, proteomic, and genomic analyses.
Multiple institutions collaborate as analytical sites for
performance of high-throughout genomics
and proteomics analyses on the samples. Clinical, demographic, outcomes,
cellular, and gene expression data from the patients and samples are highly
integrated into useful information for analysis
and informatics. There is also an administration
infrastructure in place that provides the foundation to support the administration,
project management, and finances of the research program.
Research programs in this section include: